Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004110 | 0.79 | HSP90AA1 (0.50) | HSP90AA1LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL9004176 | 0.78 | CHRM1 (0.39) | HSP90AA1LTA4HTSHRBCHEACHE | |
| SCHEMBL9004071 | 0.77 | HTR2A (0.48) | TSHRBCHEACHECYP1A2CYP2D6 | |
| SCHEMBL9004134 | 0.74 | CHRM1 (0.41) | HSP90AA1LTA4HPSMB1PSMB5ACHE | |
| SCHEMBL9004150 | 0.74 | SIGMAR1 (0.43) | HSP90AA1HRH3 | |
| SCHEMBL6548852 | 0.73 | HSP90AA1 (0.51) | HSP90AA1LTA4HBCHEACHEMAOB | |
| SCHEMBL6548849 | 0.73 | HSP90AA1 (0.51) | HSP90AA1LTA4HBCHEACHEMAOB | |
| SCHEMBL9004061 | 0.72 | HRH3 (0.43) | BCHEACHEMAOBSMN1; SMN2HRH3 | |
| SCHEMBL9412241 | 0.72 | HRH3 (0.43) | BCHEACHEMAOBHRH3 | |
| SCHEMBL9004099 | 0.72 | HRH3 (0.43) | BCHEACHEMAOBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |