Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004099 | 0.90 | HRH3 (0.43) | HRH3MAOBBCHEACHESLC6A4 | |
| SCHEMBL9412241 | 0.90 | HRH3 (0.43) | HRH3MAOBBCHEACHESLC6A4 | |
| SCHEMBL9004074 | 0.89 | HRH3 (0.41) | HRH3MAOBBCHEACHESLC6A4 | |
| SCHEMBL9004176 | 0.84 | CHRM1 (0.39) | HRH3MAOBBCHEACHESLC6A4 | |
| SCHEMBL9004150 | 0.82 | SIGMAR1 (0.43) | HRH3MEN1KMT2A | |
| SCHEMBL9004170 | 0.80 | KEAP1 (0.43) | HRH3SMN1; SMN2LMNAKMT2A | |
| SCHEMBL9004110 | 0.78 | HSP90AA1 (0.50) | HRH3SMN1; SMN2MAOBBCHEACHE | |
| SCHEMBL9004060 | 0.78 | HRH3 (0.44) | HRH3MAOBSLC6A4MEN1KMT2A | |
| SCHEMBL9004137 | 0.73 | POLB (0.44) | SMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL9004097 | 0.73 | LTA4H (0.41) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |