Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004074 | 0.82 | HRH3 (0.41) | SIGMAR1HRH3CHRM2CHRM4MEN1 | |
| SCHEMBL9004099 | 0.82 | HRH3 (0.43) | SIGMAR1HRH3CHRM2CHRM4CHRM1 | |
| SCHEMBL9412241 | 0.82 | HRH3 (0.43) | SIGMAR1HRH3CHRM2CHRM4CHRM1 | |
| SCHEMBL9004061 | 0.82 | HRH3 (0.43) | HRH3MEN1KMT2A | |
| SCHEMBL9004087 | 0.81 | SIGMAR1 (0.50) | SIGMAR1DRD3HRH3NPC1RAB9A | |
| SCHEMBL9004170 | 0.80 | KEAP1 (0.43) | HRH3NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL9004110 | 0.80 | HSP90AA1 (0.50) | HRH3ALDH1A1HSP90AA1 | |
| SCHEMBL9004139 | 0.79 | BCHE (0.46) | SIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL9004176 | 0.75 | CHRM1 (0.39) | DRD3HRH3CHRM2CHRM1HSP90AA1 | |
| SCHEMBL9004085 | 0.75 | BCHE (0.46) | SIGMAR1NPC1RAB9ACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |