Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004060 | 0.84 | HRH3 (0.44) | HRH3MAOBHRH1KCNH2 | |
| SCHEMBL9004134 | 0.82 | CHRM1 (0.41) | HSP90AA1HRH3LTA4HACHEMAOB | |
| SCHEMBL6548849 | 0.81 | HSP90AA1 (0.51) | HSP90AA1HRH3LTA4HBCHEACHE | |
| SCHEMBL6548852 | 0.81 | HSP90AA1 (0.51) | HSP90AA1HRH3LTA4HBCHEACHE | |
| SCHEMBL9004150 | 0.80 | SIGMAR1 (0.43) | HSP90AA1HRH3ALDH1A1 | |
| SCHEMBL9004097 | 0.79 | LTA4H (0.41) | HRH3LTA4HKDM4E | |
| SCHEMBL9004072 | 0.79 | HSP90AA1 (0.48) | HSP90AA1HRH3LTA4HBCHEACHE | |
| SCHEMBL9004061 | 0.78 | HRH3 (0.43) | HRH3BCHEACHEMAOBSMN1; SMN2 | |
| SCHEMBL9412241 | 0.78 | HRH3 (0.43) | HRH3BCHEACHEMAOBHRH1 | |
| SCHEMBL9004099 | 0.78 | HRH3 (0.43) | HRH3BCHEACHEMAOBHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |