Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 9/20 | 0.51 |
| ▸ | ACHE | P22303 | 8/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004102 | 0.92 | HTR2A (0.51) | BCHEACHEHTR2AHTR2CHTR2B | |
| SCHEMBL9004126 | 0.90 | BCHE (0.49) | BCHEACHEHTR2AHTR2CHTR2B | |
| SCHEMBL9004139 | 0.84 | BCHE (0.46) | BCHEACHEHTR2AHTR2CHTR2B | |
| SCHEMBL9004095 | 0.84 | BCHE (0.53) | BCHEACHEHTR2AHTR2CHTR2B | |
| SCHEMBL9004100 | 0.79 | HTR2A (0.46) | ACHEHTR2AHTR2CHTR2BLMNA | |
| SCHEMBL9004071 | 0.78 | HTR2A (0.48) | BCHEACHEHTR2AHTR2CHTR2B | |
| SCHEMBL9004155 | 0.78 | LMNA (0.51) | BCHEHTR2AHTR2CHTR2BLMNA | |
| SCHEMBL9004119 | 0.77 | MAOB (0.39) | BCHEACHEHTR2AHTR2CHTR2B | |
| SCHEMBL28936379 | 0.75 | MAOB (0.48) | LMNASMN1; SMN2MAOBMEN1CYP2D6 | |
| SCHEMBL9004105 | 0.73 | BCHE (0.49) | BCHEACHEHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |