Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004076 | 0.89 | MCHR1 (0.46) | LMNASMN1; SMN2GSK3BBCHEF3 | |
| SCHEMBL9004100 | 0.86 | HTR2A (0.46) | LMNASMN1; SMN2HTR2AHTR2CHTR2B | |
| SCHEMBL9004102 | 0.85 | HTR2A (0.51) | HTR2AHTR2CHTR2BBCHEMAOB | |
| SCHEMBL9004093 | 0.78 | BCHE (0.51) | LMNASMN1; SMN2HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL9420988 | 0.77 | HTR2A (0.63) | LMNASMN1; SMN2HTR2AHTR2CHTR2B | |
| SCHEMBL9004104 | 0.76 | TRPA1 (0.66) | LMNASMN1; SMN2GSK3BF3THRB | |
| SCHEMBL9004121 | 0.76 | HTR2A (0.45) | LMNASMN1; SMN2HTR2AHTR2CHTR2B | |
| SCHEMBL9004115 | 0.76 | HTR2A (0.45) | LMNASMN1; SMN2HTR2AHTR2CHTR2B | |
| SCHEMBL9004122 | 0.76 | HTR2A (0.45) | LMNASMN1; SMN2HTR2AHTR2CHTR2B | |
| Oxalic Acid SCHEMBL9420998 | 0.76 | HTR2A (0.55) | LMNASMN1; SMN2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |