Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.53 |
| ▸ | ACHE | P22303 | 6/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004093 | 0.84 | BCHE (0.51) | BCHEACHEHTR2AHTR2CHTR2B | |
| SCHEMBL9004126 | 0.82 | BCHE (0.49) | BCHEACHEHTR2AHTR2CHTR2B | |
| SCHEMBL9004139 | 0.79 | BCHE (0.46) | BCHEACHEHTR2AHTR2CHTR2B | |
| SCHEMBL4961384 | 0.76 | TBXA2R (0.49) | LSS | |
| SCHEMBL9004133 | 0.76 | ALOX15 (0.45) | BCHEACHEALOX15LMNASMN1; SMN2 | |
| SCHEMBL9004087 | 0.76 | SIGMAR1 (0.50) | ALOX15RAB9ASIGMAR1MEN1KMT2A | |
| SCHEMBL9004102 | 0.75 | HTR2A (0.51) | BCHEACHEALOX15HTR2AHTR2C | |
| SCHEMBL4018802 | 0.74 | LMNA (0.71) | BCHEACHEHTR2AHTR2CLMNA | |
| SCHEMBL4018801 | 0.74 | LMNA (0.71) | BCHEACHEHTR2AHTR2CLMNA | |
| Hydrochloric Acid SCHEMBL9420981 | 0.74 | HTR2A (0.62) | BCHEACHEHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |