Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.45 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004187 | 0.85 | TRPA1 (0.71) | TRPA1ALOX15NPC1L3MBTL1TDP1 | |
| SCHEMBL13816398 | 0.85 | TRPA1 (0.50) | TRPA1ALOX15NPC1L3MBTL1TDP1 | |
| SCHEMBL1499368 | 0.81 | TRPA1 (1.00) | TRPA1NPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9004135 | 0.81 | TRPA1 (0.70) | TRPA1NPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4451132 | 0.81 | TRPA1 (1.00) | TRPA1NPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3675503 | 0.81 | TRPA1 (0.65) | TRPA1ALOX15NPC1LMNASMN1; SMN2 | |
| SCHEMBL4457739 | 0.81 | TRPA1 (1.00) | TRPA1NPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3675504 | 0.81 | TRPA1 (0.65) | TRPA1ALOX15NPC1LMNASMN1; SMN2 | |
| SCHEMBL1499367 | 0.81 | TRPA1 (1.00) | TRPA1NPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9004180 | 0.80 | ALOX15 (0.53) | TRPA1ALOX15NPC1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| CN-1100716-A | Basic ethers and process for the preparation thereof | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-03-29 | — | — | CN | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |