Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16863790 | 0.83 | BRD4 (0.47) | KMT2ABRD4MAPTCYP1A2CYP2C19 | |
| SCHEMBL19030688 | 0.81 | BRD4 (0.61) | KMT2ABRD4MAPTCYP1A2CYP2C19 | |
| SCHEMBL31694220 | 0.81 | LMNA (0.43) | KMT2ABRD4MAPTCA12CA1 | |
| SCHEMBL29240343 | 0.81 | KMT2A (0.44) | KMT2ABRD4MAPTCYP1A2CYP2C19 | |
| SCHEMBL20436332 | 0.81 | HTT (0.49) | KMT2ABRD4MAPTCYP1A2CYP2C19 | |
| SCHEMBL29706799 | 0.81 | BRD4 (0.61) | KMT2ABRD4MAPTCYP1A2CYP2C19 | |
| SCHEMBL32683704 | 0.81 | LMNA (0.43) | KMT2ABRD4MAPTCA12CA1 | |
| SCHEMBL15323907 | 0.79 | KMT2A (0.46) | KMT2ABRD4MAPTCYP1A2CYP2C19 | |
| SCHEMBL32683362 | 0.78 | ALDH1A1 (0.39) | KMT2ABRD4MAPTXBP1HTT | |
| SCHEMBL23612428 | 0.77 | KMT2A (0.37) | KMT2ABRD4MAPTXBP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103951632-B | The preparation method of 2,2,7-tri-fluoro-2H-1,4-benzoxazine-3 (4H)-one compounds | BEIJING NUTRICHEM COMPANY LIMITED (CN) | 2016-03-16 | — | — | CN | claimed |
| CN-108727367-B | Benzoxazinone compound containing pyridopyrimidinedione, preparation method and application thereof, and herbicide composition | 山东先达农化股份有限公司 | 2021-01-05 | — | — | CN | disclosed |
| EP-2651226-B1 | HERBICIDAL COMPOSITIONS | BASF SE (DE) | 2016-11-23 | — | — | EP | disclosed |
| EP-2651226-B1 | HERBICIDAL COMPOSITIONS | BASF SE (DE) | 2016-11-23 | — | — | EP | disclosed |
| CN-103951632-B | The preparation method of 2,2,7-tri-fluoro-2H-1,4-benzoxazine-3 (4H)-one compounds | BEIJING NUTRICHEM COMPANY LIMITED (CN) | 2016-03-16 | — | — | CN | disclosed |
| CN-103951632-B | The preparation method of 2,2,7-tri-fluoro-2H-1,4-benzoxazine-3 (4H)-one compounds | BEIJING NUTRICHEM COMPANY LIMITED (CN) | 2016-03-16 | — | — | CN | disclosed |
| US-9220268-B2 | Herbicidal benzoxazinones | BASF SE (DE) | 2015-12-29 | — | — | US | disclosed |
| US-9220268-B2 | Herbicidal benzoxazinones | BASF SE (DE) | 2015-12-29 | — | — | US | disclosed |
| US-9220268-B2 | Herbicidal benzoxazinones | BASF SE (DE) | 2015-12-29 | — | — | US | disclosed |
| US-20150250181-A1 | Herbicidal Benzoxazinones | BASF SE (DE) | 2015-09-10 | — | — | US | disclosed |
| US-20120100991-A1 | HERBICIDAL BENZOXAZINONES | BASF SE (DE) | 2012-04-26 | — | — | US | disclosed |
| EP-2443102-A1 | HERBICIDAL BENZOXAZINONES | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| WO-2012041789-A1 | HERBICIDAL BENZOXAZINONES | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012041789-A1 | HERBICIDAL BENZOXAZINONES | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |
| WO-2011057935-A1 | 3-(3,4-DIHYDRO-2H-BENZO [1,4]OXAZIN-6-YL)-1H-PYRIMIDIN-2,4-DIONE COMPOUNDS AS HERBICIDES | BASF SE (DE) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011057935-A1 | 3-(3,4-DIHYDRO-2H-BENZO [1,4]OXAZIN-6-YL)-1H-PYRIMIDIN-2,4-DIONE COMPOUNDS AS HERBICIDES | BASF SE (DE) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011012622-A1 | BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF GLYTL MEDIATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2011-02-03 | — | — | WO | disclosed |
| WO-2011012622-A1 | BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF GLYTL MEDIATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2011-02-03 | — | — | WO | disclosed |
| WO-2010145992-A1 | HERBICIDAL BENZOXAZINONES | BASF SE (DE) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010145992-A1 | HERBICIDAL BENZOXAZINONES | BASF SE (DE) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100991-A1 | HERBICIDAL BENZOXAZINONES | CYP4X1, AOX1, PRDX5 | KMT2A 2398/4885BRD4 1887/4885MAPT 4095/4885 |
| US-20150250181-A1 | Herbicidal Benzoxazinones | CYP4X1, AOX1, PRDX5 | KMT2A 2398/4885BRD4 1887/4885MAPT 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.