Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28249284 | 0.83 | HPGD (0.47) | HPGDNPC1RAB9AMAPK1HTT | |
| SCHEMBL6469287 | 0.81 | LPL (0.44) | HPGDNPC1RAB9AMAPK1HTT | |
| SCHEMBL9272804 | 0.79 | HPGD (0.48) | HPGDNPC1RAB9AMAPK1HTT | |
| SCHEMBL20467130 | 0.77 | IDO1 (0.45) | HPGDNPC1RAB9AMAPK1HTT | |
| SCHEMBL28181909 | 0.75 | PTGS2 (0.53) | PTGS2CYP3A4GPR84ALDH1A1HSD17B10 | |
| SCHEMBL22861012 | 0.75 | NPC1 (0.40) | HPGDNPC1RAB9AMAPK1HTT | |
| SCHEMBL2002090 | 0.74 | HPGD (0.61) | HPGDNPC1RAB9AMAPK1HTT | |
| SCHEMBL45290 | 0.74 | GABRA1 (0.38) | — | |
| SCHEMBL27369768 | 0.72 | NPC1 (0.46) | HPGDNPC1RAB9AMAPK1HTT | |
| SCHEMBL27994037 | 0.71 | HPGD (0.58) | HPGDNPC1RAB9AMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580935-A | REACTING A LIVING POLYMER HAVING A TERMINAL HALIDE WITH AN ALKYLSILYLPSEUDOHALIDE, E.G A SILYLMONO-, DI- OR TRIAZIDE; OIL ADDITIVES; LUBRICANTS; POLYURETHANES; EPOXY RESIN | EXXON CHEMICAL PATENTS INC. (US) | 1996-12-03 | — | — | US | disclosed |
| US-5523359-A | A LIVING POLYMER CONSISTING OF HYDROCARBON MONOMERS HAVING HALIDE GROUP WITH SILYL ENOL ETHER | EXXON CHEMICAL PATENTS INC. (US) | 1996-06-04 | — | — | US | disclosed |