SCHEMBL9004769

SCHEMBL9004769

FC(F)(F)c1ccccc1[Ti](C1=CC=CC1)C1=CC=CC1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
P2RX7 Q99572 1/20 0.30
HTR2C P28335 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiocyanic Acid SCHEMBL9004779 0.91 AR (0.30)
SCHEMBL9004830 0.85 HSD11B1 (0.33) HSD11B1P2RX7
Hydrochloric Acid SCHEMBL9004732 0.78 CES2 (0.36)
SCHEMBL8961799 0.76 HSD11B1 (0.32) HSD11B1MEN1KMT2A
Hydrochloric Acid SCHEMBL9005137 0.74 HSD11B1 (0.31) HSD11B1ALDH1A1POLBTDP1L3MBTL1
Hydrochloric Acid SCHEMBL9547761 0.74 HTR2C (0.31) HSD11B1ALDH1A1POLBTDP1L3MBTL1
Fluoride SCHEMBL9004753 0.74 HSD11B1 (0.31) HSD11B1P2RX7
Hydrochloric Acid SCHEMBL9005001 0.74 EPHX2 (0.34) MEN1KMT2A
SCHEMBL27384908 0.70 TRPA1 (0.32)
SCHEMBL3243312 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5510539-A LIQUID KETALS; LONG DARK STORAGE STABILITY CIBA-GEIGY CORPORATION (US) 1996-04-23 US disclosed
US-5288917-A Benzil ketals; end-capped polyoxyyethylene glycol; mixed with titanocene-type initiators CIBA-GEIGY CORPORATION (US) 1994-02-22 US disclosed