SCHEMBL9004830

SCHEMBL9004830

FC(F)(F)c1cccc([Ti](C2=CC=CC2)C2=CC=CC2)c1C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.33
P2RX7 Q99572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9004769 0.85 HSD11B1 (0.31) HSD11B1P2RX7
Fluoride SCHEMBL9004753 0.74 HSD11B1 (0.31) HSD11B1P2RX7
Hydrochloric Acid SCHEMBL9004732 0.71 CES2 (0.36)
SCHEMBL27384908 0.70 TRPA1 (0.32)
Hydrochloric Acid SCHEMBL9005001 0.68 EPHX2 (0.34)
SCHEMBL6910589 0.66
SCHEMBL2000756 0.66 HSD11B1 (0.46) HSD11B1P2RX7
Lithium SCHEMBL5691154 0.64 HSD11B1 (0.44) HSD11B1P2RX7
SCHEMBL7602903 0.63 HSD11B1 (0.41) HSD11B1P2RX7
SCHEMBL14932033 0.63 HSD11B1 (0.41) HSD11B1P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5510539-A LIQUID KETALS; LONG DARK STORAGE STABILITY CIBA-GEIGY CORPORATION (US) 1996-04-23 US disclosed
US-5288917-A Benzil ketals; end-capped polyoxyyethylene glycol; mixed with titanocene-type initiators CIBA-GEIGY CORPORATION (US) 1994-02-22 US disclosed