Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.55 |
| ▸ | NPC1 | O15118 | 9/20 | 0.55 |
| ▸ | PKM | P14618 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1976586 | 0.80 | NPC1 (0.50) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL1976587 | 0.80 | NPC1 (0.50) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL27197722 | 0.80 | RAB9A (0.59) | RAB9ANPC1PKMSMN1; SMN2MEN1 | |
| SCHEMBL11764046 | 0.79 | ALDH1A1 (0.44) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL11518190 | 0.78 | KDM4E (0.42) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL10505863 | 0.77 | CHRNB2 (0.42) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL11129959 | 0.77 | LMNA (0.37) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL10859330 | 0.77 | MEN1 (0.67) | RAB9ANPC1CYP1A2MEN1KMT2A | |
| SCHEMBL4729346 | 0.76 | CYP1A2 (0.48) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL4728039 | 0.76 | CYP2C9 (0.48) | RAB9ANPC1PKMSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013656-A | PROCESS FOR THE PREPARATION OF PYRIDYLAMINO-METHYLENEMALONIC ACID DERIVATIVES | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | claimed |
| US-5576320-A | 1-heteruarylazetidines and -pyrrolidines, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-11-19 | — | — | US | disclosed |
| US-5565474-A | 1-heteroarylazetidines and -pyrrolidines process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-10-15 | — | — | US | disclosed |
| US-5410057-A | 1-heteroarylazetidines and -pyrrolidines | SANOFI (FR) | 1995-04-25 | — | — | US | disclosed |
| US-4456752-A | REACTING A HYDRAZINE WITH DIHALOGEN SUBSTITUTED PYRIDO(1,2-A)PYRIMIDINE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1984-06-26 | — | — | US | disclosed |
| US-4260612-A | Antiallergic nitrogen bridge-head compounds | CHINOIN GYOGYSZER ES VECYESZETI TERMEKEK GYARA RT. (HU) | 1981-04-07 | — | — | US | disclosed |
| US-4013656-A | PROCESS FOR THE PREPARATION OF PYRIDYLAMINO-METHYLENEMALONIC ACID DERIVATIVES | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-4013656-A | PROCESS FOR THE PREPARATION OF PYRIDYLAMINO-METHYLENEMALONIC ACID DERIVATIVES | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-3907798-A | Preparation of 4H-pyrido{8 1,2-a{9 pyrimidin-4-ones from cyclic alkylidene 2-pyridylaminomethylenemalonates | STERLING DRUG INC | 1975-09-23 | — | — | US | disclosed |