Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.48 |
| ▸ | SKP1 | P63208 | 2/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 8/20 | 0.43 |
| ▸ | ACACA | Q13085 | 7/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005360 | 0.84 | CKS1B (0.44) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL7388880 | 0.84 | CKS1B (0.52) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL7394063 | 0.83 | CKS1B (0.43) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL9005362 | 0.82 | CKS1B (0.43) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL23168014 | 0.78 | TRPV3 (0.52) | CKS1BSKP1SKP2HSD11B1L3MBTL1 | |
| SCHEMBL4703939 | 0.74 | CKS1B (0.62) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL25766607 | 0.74 | CKS1B (0.62) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL7391751 | 0.72 | HSD11B1 (0.42) | ACACBHSD11B1 | |
| Hydrochloric Acid SCHEMBL9005386 | 0.71 | HSD11B1 (0.41) | ACACBHSD11B1 | |
| SCHEMBL7391345 | 0.70 | DRD2 (0.50) | CKS1BSKP1SKP2ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565474-A | 1-heteroarylazetidines and -pyrrolidines process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-10-15 | — | — | US | disclosed |
| US-5410057-A | 1-heteroarylazetidines and -pyrrolidines | SANOFI (FR) | 1995-04-25 | — | — | US | disclosed |