Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 11/20 | 0.39 |
| ▸ | ACACA | Q13085 | 8/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005360 | 0.83 | CKS1B (0.44) | CKS1BSKP1SKP2DRD2ACACB | |
| SCHEMBL9005449 | 0.82 | CKS1B (0.48) | CKS1BSKP1SKP2DRD2ACACB | |
| SCHEMBL7394063 | 0.82 | CKS1B (0.43) | CKS1BSKP1SKP2DRD2ACACB | |
| SCHEMBL7389331 | 0.81 | NAMPT (0.47) | CKS1BSKP1SKP2DRD2ACACB | |
| Oxalic Acid SCHEMBL9005359 | 0.74 | MGLL (0.43) | DRD2ACACBDRD4 | |
| SCHEMBL7391156 | 0.72 | CTSS (0.40) | DRD2DRD4 | |
| SCHEMBL2956934 | 0.72 | KDM4A (0.47) | — | |
| Hydrochloric Acid SCHEMBL9005437 | 0.71 | CTSS (0.39) | DRD2DRD4 | |
| SCHEMBL13217212 | 0.70 | NQO2 (0.47) | CKS1BSKP1SKP2 | |
| SCHEMBL3486734 | 0.69 | GPR119 (0.69) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565474-A | 1-heteroarylazetidines and -pyrrolidines process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-10-15 | — | — | US | disclosed |
| US-5410057-A | 1-heteroarylazetidines and -pyrrolidines | SANOFI (FR) | 1995-04-25 | — | — | US | disclosed |