Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114094 | 0.80 | CA1 (0.46) | ESR1ESR2 | |
| SCHEMBL12802084 | 0.77 | FFAR4 (0.46) | FFAR4 | |
| SCHEMBL1609581 | 0.77 | — | — | |
| SCHEMBL8060136 | 0.76 | ALDH1A1 (0.36) | — | |
| SCHEMBL1610949 | 0.73 | FFAR4 (0.31) | FFAR4 | |
| SCHEMBL10424337 | 0.72 | RAPGEF4 (0.33) | RAPGEF4ESR1ESR2 | |
| SCHEMBL16105713 | 0.71 | RAPGEF4 (0.43) | RAPGEF4FFAR4ESR1ESR2 | |
| SCHEMBL16105836 | 0.71 | SHBG (0.46) | RAPGEF4ESR1ESR2 | |
| SCHEMBL7687745 | 0.70 | SLC6A2 (0.41) | ESR1ESR2 | |
| SCHEMBL599609 | 0.69 | RAPGEF4 (0.41) | RAPGEF4ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |