SCHEMBL28114094

SCHEMBL28114094

C[CH]Cc1cc(C)c(O)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
PTGS1 P23219 8/20 0.44
PTGS2 P35354 8/20 0.44
SHBG P04278 1/20 0.42
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
ALOX5 P09917 6/20 0.41
HMGB1 P09429 1/20 0.39
CXCL12 P48061 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2B6 P20813 1/20 0.38
TTR P02766 1/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
CISD1 Q9NZ45 1/20 0.37
EEF2K O00418 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4799617 0.81 CA1 (0.46) CA1CA2PTGS1PTGS2SHBG
SCHEMBL900547 0.80 RAPGEF4 (0.31) ESR1ESR2
SCHEMBL719239 0.79 XDH (0.47) CA1CA2PTGS1PTGS2SHBG
SCHEMBL11172000 0.77 CA1 (0.42) CA1CA2PTGS1PTGS2SHBG
SCHEMBL8306892 0.75 CA1 (0.50) CA1CA2PTGS1PTGS2SHBG
SCHEMBL3801816 0.74 PTGS1 (0.68) CA1CA2PTGS1PTGS2SHBG
SCHEMBL68876 0.74 SHBG (0.67) CA1CA2PTGS1PTGS2SHBG
SCHEMBL1121332 0.72 SHBG (0.64) CA1CA2PTGS1PTGS2SHBG
SCHEMBL1023068 0.72 PTGS1 (0.55) CA1CA2PTGS1PTGS2SHBG
SCHEMBL8060136 0.72 ALDH1A1 (0.36) MAOACISD1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107207864-A Flame retardant molding composition polycarbonate block cocondensation, containing glass fibre comprising silicone-containing 科思创德国股份有限公司 2017-09-26 CN disclosed
CN-107207863-A Flame-resistant moulding compositions containing silicone-containing polycarbonate block cocondensates 科思创德国股份有限公司 2017-09-26 CN disclosed
CN-104619474-B Method for producing plastic molded parts with UV-curing paint and the molded parts 科思创德国股份有限公司 2016-12-21 CN disclosed