Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 2/20 | 0.42 |
| ▸ | KMO | O15229 | 6/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570966 | 0.83 | NPC1 (0.42) | KIF20BAHRKMONOTUMNPC1 | |
| SCHEMBL18041475 | 0.79 | IDO1 (0.45) | KMONOTUM | |
| SCHEMBL23410559 | 0.77 | KDM4E (0.44) | NPC1RAB9ALMNAMEN1CRHBP | |
| SCHEMBL19627018 | 0.74 | AHR (0.46) | AHRKMONOTUMNPC1RAB9A | |
| SCHEMBL9080400 | 0.72 | KDM4E (0.49) | NPC1RAB9ALMNAHPGDMEN1 | |
| SCHEMBL9050978 | 0.72 | KIF11 (0.47) | NPC1RAB9A | |
| SCHEMBL9048277 | 0.72 | AHR (0.41) | KIF20BAHRNOTUMNPC1RAB9A | |
| SCHEMBL2944949 | 0.70 | MAPK13 (0.49) | AHRKMONOTUMNPC1RAB9A | |
| SCHEMBL3557053 | 0.70 | KMO (0.53) | KIF20BAHRKMOTTRNPC1 | |
| SCHEMBL31305411 | 0.70 | MAPK13 (0.49) | AHRKMONOTUMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736013-A1 | N-SUBSTITUTED ARYL TRIFLUOROMETHYL IMIDAZOLES | BAYER AG (DE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017390-A1 | N-SUBSTITUTED ARYL TRIFLUOROMETHYL IMIDAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-06-29 | — | — | WO | disclosed |