Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557279 | 0.84 | ACHE (0.44) | ACHEALDH1A1ESR2PRKCZKDM1A | |
| SCHEMBL1005966 | 0.82 | ACHE (0.47) | ACHEALDH1A1TSHRESR2PRKCZ | |
| SCHEMBL14796720 | 0.72 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ESR2PRKCZ | |
| SCHEMBL14192801 | 0.71 | ACHE (0.38) | ACHEKDM1A | |
| SCHEMBL28189819 | 0.70 | ACHE (0.55) | ACHEALDH1A1ESR2KDM1ADEGS1 | |
| SCHEMBL18559749 | 0.69 | KDM1A (0.54) | ACHEALDH1A1ESR2KDM1ADEGS1 | |
| SCHEMBL18559915 | 0.69 | KDM1A (0.54) | ACHEALDH1A1ESR2KDM1ADEGS1 | |
| SCHEMBL9861782 | 0.68 | ESR2 (0.41) | ACHETSHRESR2KDM1ADEGS1 | |
| SCHEMBL13609953 | 0.67 | KDM1A (0.42) | ACHETSHRESR2KDM1AESR1 | |
| Ammonia Solution, Strong SCHEMBL268752 | 0.67 | KDM1A (0.52) | ACHEALDH1A1ESR2KDM1ADEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736561-A2 | Dihydroxy compound mixtures and polymers thereof | GENERAL ELECTRIC COMPANY (US) | 1996-10-09 | — | — | EP | disclosed |