Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 3/20 | 0.35 |
| ▸ | CDK2 | P24941 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006267 | 0.73 | MAP4K4 (0.46) | KMT2AGAAMAPTMEN1POLB | |
| SCHEMBL11668218 | 0.70 | ALDH1A1 (0.45) | KMT2AGAAMAPTMEN1POLB | |
| SCHEMBL9686737 | 0.70 | GAA (0.63) | KMT2AGAAMAPTMEN1POLB | |
| SCHEMBL988218 | 0.69 | KMT2A (0.50) | KMT2AGAAMAPTMEN1POLB | |
| SCHEMBL28237515 | 0.67 | KMT2A (0.42) | KMT2AGAAMAPTMEN1TLR8 | |
| SCHEMBL8523726 | 0.66 | KDM4E (0.42) | KMT2AGAAMAPTMEN1TLR8 | |
| SCHEMBL29034746 | 0.66 | ALDH1A1 (0.42) | KMT2AGAAMAPTMEN1POLB | |
| SCHEMBL8672800 | 0.65 | TLR8 (0.49) | KMT2AGAAMAPTMEN1TLR8 | |
| SCHEMBL8213737 | 0.65 | TLR8 (0.49) | KMT2AGAAMAPTMEN1TLR8 | |
| SCHEMBL6904196 | 0.65 | ALDH1A1 (0.40) | KMT2AGAAMAPTMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506236-A | TREATING HERPES VIRUS INFECTIONS | SCHERING CORPORATION | 1996-04-09 | — | — | US | disclosed |