Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8838002 | 0.85 | HRH3 (0.53) | ALDH1A1MAPTKDM4EPKMKMT2A | |
| SCHEMBL11214293 | 0.84 | HTR1A (0.56) | ALDH1A1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL1099464 | 0.83 | KDM4E (0.66) | ALDH1A1MAPTKDM4EPKMHDAC4 | |
| SCHEMBL6885691 | 0.82 | KMT2A (0.61) | ALDH1A1MAPTKDM4EKMT2AGAA | |
| SCHEMBL25409382 | 0.81 | GAA (0.49) | RAD52ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL27971265 | 0.81 | RAD52 (0.46) | RAD52ALDH1A1MAPTKDM4EPKM | |
| SCHEMBL11211339 | 0.80 | ATM (0.53) | ALDH1A1GAATSHRATMLMNA | |
| SCHEMBL23340098 | 0.79 | ADRA2A (0.54) | RAD52ALDH1A1MAPTKDM4EPKM | |
| SCHEMBL3967181 | 0.78 | SLC6A9 (0.40) | ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL24220960 | 0.78 | SLC6A9 (0.40) | ALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486517-A | Benzimidazoles and imidazopyridines as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| US-4457931-A | ANTISPASMODIC | SELVI & C. S.P.A. (IT) | 1984-07-03 | — | — | US | disclosed |