Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693481 | 0.88 | HTR1A (0.56) | HTR1AHTR2AHTR7HTR6CA12 | |
| SCHEMBL11955707 | 0.86 | HTR3E (0.58) | HTR1AHTR2AHTR7HTR6LMNA | |
| Hydrochloric Acid SCHEMBL9993047 | 0.85 | CHRNA1 (0.62) | CA12CA1CA9MEN1KMT2A | |
| SCHEMBL9006342 | 0.84 | RAD52 (0.52) | MEN1KMT2ALMNATSHRNPSR1 | |
| SCHEMBL10764513 | 0.83 | HTR1A (0.55) | HTR1AHTR2AHTR7HTR6CA12 | |
| SCHEMBL6885691 | 0.83 | KMT2A (0.61) | MEN1KMT2AALDH1A1 | |
| SCHEMBL10763272 | 0.82 | ALDH1A1 (0.57) | HTR1AHTR2AHTR7HTR6MEN1 | |
| SCHEMBL4355720 | 0.82 | ALDH1A1 (0.56) | HTR1AHTR2AHTR7HTR6MEN1 | |
| SCHEMBL4255355 | 0.80 | ALDH1A1 (0.59) | HTR1AHTR2AHTR7HTR6LMNA | |
| SCHEMBL6412443 | 0.79 | MCOLN2 (0.60) | MEN1KMT2ALMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325952-A | Method of treating abstinence syndrome with cycloaklyltriazoles | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO (IT) | 1982-04-20 | — | — | US | disclosed |
| US-4307095-A | PSYCHOTHERAPY AND ANTIGLAUCOMA AGENTS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1981-12-22 | — | — | US | disclosed |
| US-4307096-A | Method of treating glaucoma with cycloalkyltriazoles | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1981-12-22 | — | — | US | disclosed |
| US-4252721-A | ANTIGLAUCOMIC AND ANTIPSYCHOTIC AGENTS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1981-02-24 | — | — | US | disclosed |