Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 12/20 | 1.00 |
| ▸ | DRD2 | P14416 | 11/20 | 1.00 |
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006339 | 0.87 | DRD3 (1.00) | DRD3DRD2ACHEDRD4 | |
| SCHEMBL601512 | 0.85 | DRD3 (1.00) | DRD3DRD2ACHE | |
| SCHEMBL9006356 | 0.84 | DRD3 (1.00) | DRD3DRD2ACHE | |
| SCHEMBL9006297 | 0.84 | DRD3 (0.89) | DRD3DRD2ACHE | |
| SCHEMBL9006337 | 0.83 | DRD3 (1.00) | DRD3DRD2ACHEDRD4 | |
| SCHEMBL9006340 | 0.83 | DRD3 (1.00) | DRD3DRD2ACHE | |
| SCHEMBL9006359 | 0.83 | DRD3 (0.85) | DRD3DRD2ACHESLC6A2SLC6A4 | |
| SCHEMBL9006348 | 0.83 | DRD3 (0.85) | DRD3DRD2ACHE | |
| SCHEMBL9260985 | 0.83 | ACHE (0.89) | DRD3DRD2ACHE | |
| SCHEMBL13033483 | 0.82 | DRD2 (0.68) | DRD3DRD2ACHEDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030659-A1 | BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINERGIC AGENTS, ESP. SELECTIVE FOR THE DOPAMINE D3 RECEPTOR | WARNER-LAMBERT COMPANY (US) | 1995-11-16 | — | — | WO | claimed |
| US-5486517-A | Benzimidazoles and imidazopyridines as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1995030659-A1 | BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINERGIC AGENTS, ESP. SELECTIVE FOR THE DOPAMINE D3 RECEPTOR | WARNER-LAMBERT COMPANY (US) | 1995-11-16 | — | — | WO | disclosed |