SCHEMBL9006503

SCHEMBL9006503

O=C(/C=C/c1ccc(Cl)cc1)/C=C/c1ccc(OC(F)=C(F)F)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.64
NPC1 O15118 2/20 0.51
ALDH1A1 P00352 2/20 0.51
LMNA P02545 2/20 0.51
MAPT P10636 2/20 0.51
RAB9A P51151 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
HTT P42858 1/20 0.51
F3 P13726 2/20 0.50
MAOB P27338 5/20 0.48
MAOA P21397 1/20 0.48
HSD11B1 P28845 2/20 0.46
CYP2D6 P10635 2/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
PKM P14618 1/20 0.45
TSHR P16473 1/20 0.45
NFKB1 P19838 1/20 0.45
MAPK1 P28482 1/20 0.45
CYP2C19 P33261 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9006511 1.00 CYP1A2 (0.64) CYP1A2NPC1ALDH1A1LMNAMAPT
SCHEMBL9006668 0.92 F3 (0.58) CYP1A2ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL9006591 0.92 F3 (0.58) CYP1A2ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL9006786 0.90 CYP1A2 (0.51) CYP1A2NPC1ALDH1A1LMNAMAPT
SCHEMBL9006782 0.90 CYP1A2 (0.51) CYP1A2NPC1ALDH1A1LMNAMAPT
SCHEMBL9006486 0.87 PTGS2 (0.44) CYP1A2NPC1ALDH1A1LMNAMAPT
SCHEMBL9006482 0.87 PTGS2 (0.44) CYP1A2NPC1ALDH1A1LMNAMAPT
SCHEMBL9006742 0.86 F3 (0.62) CYP1A2ALDH1A1MAPTRAB9AF3
SCHEMBL9006741 0.86 F3 (0.62) CYP1A2ALDH1A1MAPTRAB9AF3
SCHEMBL9006616 0.86 F3 (0.59) CYP1A2NPC1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US claimed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP claimed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US claimed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO claimed
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US disclosed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP disclosed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US disclosed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO disclosed