SCHEMBL9006741

SCHEMBL9006741

O=C(/C=C/c1ccc(O)cc1)/C=C/c1ccc(OC(F)=C(F)F)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F3 P13726 4/20 0.62
TYR P14679 3/20 0.62
HSD11B1 P28845 2/20 0.62
CYP2D6 P10635 1/20 0.62
CYP2C9 P11712 1/20 0.62
STAT3 P40763 1/20 0.55
GSK3B P49841 2/20 0.50
BACE1 P56817 2/20 0.50
TLR9 Q9NR96 1/20 0.50
BCHE P06276 2/20 0.48
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA7 P43166 2/20 0.47
CA9 Q16790 2/20 0.47
CA14 Q9ULX7 2/20 0.47
AKR1B10 O60218 2/20 0.47
AKR1B1 P15121 2/20 0.47
ESR1 P03372 1/20 0.47
CA3 P07451 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9006742 1.00 F3 (0.62) F3TYRHSD11B1CYP2D6CYP2C9
SCHEMBL9006668 0.94 F3 (0.58) F3TYRHSD11B1CYP2D6CYP2C9
SCHEMBL9006591 0.94 F3 (0.58) F3TYRHSD11B1CYP2D6CYP2C9
SCHEMBL9006693 0.88 HSD11B1 (0.66) F3TYRHSD11B1CYP2D6CYP2C9
SCHEMBL9006612 0.88 F3 (0.59) F3TYRHSD11B1CYP2D6CYP2C9
SCHEMBL9006616 0.88 F3 (0.59) F3TYRHSD11B1CYP2D6CYP2C9
SCHEMBL9006689 0.88 HSD11B1 (0.66) F3TYRHSD11B1CYP2D6CYP2C9
SCHEMBL9006417 0.87 APP (0.50) TYRCYP2D6CYP2C9CA12CA1
SCHEMBL9006421 0.87 APP (0.50) TYRCYP2D6CYP2C9CA12CA1
SCHEMBL25214444 0.87 F3 (0.66) F3BCHEESR1PKMESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US claimed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP claimed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US claimed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO claimed
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US disclosed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP disclosed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US disclosed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO disclosed