Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722508 | 0.91 | OPRM1 (0.42) | LTA4HSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL2720750 | 0.90 | SLC6A3 (0.43) | SMN1; SMN2MEN1KMT2AMAPTPSMD14 | |
| SCHEMBL900449 | 0.87 | CYP2D6 (0.42) | LTA4HSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL901252 | 0.86 | LTA4H (0.45) | LTA4HSMN1; SMN2HTR1ASLC6A2SLC6A3 | |
| SCHEMBL2720478 | 0.86 | EBP (0.42) | LTA4HSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL901074 | 0.86 | ALDH1A1 (0.46) | LTA4HSMN1; SMN2MEN1KMT2AHTR1A | |
| SCHEMBL2722120 | 0.84 | KCNH2 (0.42) | LTA4HSMN1; SMN2MAPTRAB9AHTR1A | |
| SCHEMBL900712 | 0.83 | CYP2D6 (0.43) | LTA4HSMN1; SMN2KMT2AMAPTRAB9A | |
| SCHEMBL2722162 | 0.83 | CYP2D6 (0.43) | LTA4HSMN1; SMN2MAPTRAB9AHTR1A | |
| Oxalic Acid SCHEMBL2720278 | 0.83 | MEN1 (0.47) | LTA4HSMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621916-A1 | BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | BIOPROJET (FR) | 2013-08-07 | — | — | EP | claimed |
| WO-2012041860-A1 | BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | BIOPROJET (FR) | 2012-04-05 | — | — | WO | claimed |