Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006818 | 0.87 | THRB (0.35) | LMNAHDAC1HDAC2HDAC4NPC1 | |
| SCHEMBL10872336 | 0.81 | SRR (0.33) | LMNABCAT2HDAC4NPC1RAB9A | |
| SCHEMBL6849682 | 0.76 | CYP3A4 (0.31) | TDP1CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL5067245 | 0.76 | HDAC1 (0.35) | LMNAHDAC1HDAC2NPC1RAB9A | |
| SCHEMBL8957775 | 0.75 | HDAC1 (0.37) | LMNAHDAC1HDAC2NPC1RAB9A | |
| SCHEMBL29007685 | 0.75 | HDAC4 (0.32) | LMNABCAT2HDAC4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5072257 | 0.75 | HDAC1 (0.34) | HDAC1HDAC2NPC1RAB9A | |
| SCHEMBL4619747 | 0.75 | HDAC4 (0.33) | LMNAHDAC1HDAC2HDAC4NPC1 | |
| Methane SCHEMBL28875106 | 0.74 | HDAC1 (0.36) | LMNAHDAC1HDAC2NPC1RAB9A | |
| SCHEMBL28658397 | 0.73 | HDAC1 (0.33) | LMNAHDAC1HDAC2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066621-A1 | SYNTHESIS, POLYMORPHS, AND PHARMACEUTICAL FORMULATION OF A FAAH INHIBITOR | N.V. Organon (NL) | 2009-06-10 | — | — | EP | disclosed |
| CN-100408556-C | Modulation of anxiety by blocking hydrolysis of arachidonoylethanolamide | UNIV CALIFORNIA (US) | 2008-08-06 | — | — | CN | disclosed |
| WO-2008022976-A1 | SYNTHESIS, POLYMORPHS, AND PHARMACEUTICAL FORMULATION OF A FAAH INHIBITOR | N.V. ORGANON (NL) | 2008-02-28 | — | — | WO | disclosed |
| CN-1729171-A | Modulation of anxiety by blocking hydrolysis of arachidonoylethanolamide | UNIV CALIFORNIA (US) | 2006-02-01 | — | — | CN | disclosed |