Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11882012 | 0.82 | MAPT (0.48) | TDP1CA1CA12CA7CA9 | |
| SCHEMBL69925 | 0.79 | TDP1 (0.52) | TDP1CA1CA12CA7CA9 | |
| SCHEMBL29403778 | 0.79 | TDP1 (0.52) | TDP1CA1CA12CA7CA9 | |
| SCHEMBL5349727 | 0.76 | CYP3A4 (0.54) | TDP1CA1CA2MAPTTP53 | |
| SCHEMBL11750586 | 0.76 | MAOA (0.43) | TDP1CA1CA12CA7CA9 | |
| SCHEMBL25170487 | 0.74 | TDP1 (0.39) | TDP1CA1CA12CA7CA9 | |
| SCHEMBL2588846 | 0.74 | TPMT (0.40) | TDP1CA1CA12CA7CA9 | |
| SCHEMBL9623295 | 0.72 | ESR1 (0.55) | TDP1CA1CA12CA7CA9 | |
| SCHEMBL7738982 | 0.71 | PDE4A (0.38) | TDP1CA1CA12CA7CA9 | |
| SCHEMBL17008599 | 0.71 | KDM4E (0.39) | TDP1CA1CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736018-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |