Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11882012 | 0.77 | MAPT (0.48) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL1049663 | 0.75 | CA2 (0.45) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL36382 | 0.75 | ALDH1A1 (0.39) | CA1TDP1CA2ESR1ESR2 | |
| SCHEMBL29370295 | 0.75 | ALDH1A1 (0.39) | CA1TDP1CA2ESR1ESR2 | |
| SCHEMBL69925 | 0.74 | TDP1 (0.52) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL29403778 | 0.74 | TDP1 (0.52) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL1567262 | 0.73 | ALOX15 (0.41) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL29778650 | 0.72 | ESR1 (0.50) | PDE4APDE4BPDE4CPDE4DTDP1 | |
| SCHEMBL4056187 | 0.71 | ESR1 (0.41) | TDP1CA2ESR1ESR2LMNA | |
| SCHEMBL9006932 | 0.71 | TDP1 (0.41) | PDE4APDE4BPDE4CPDE4DCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001000707-A1 | LIGHT DIFFUSING BLOCK COPOLYCARBONATES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |
| EP-1063253-A1 | Light diffusing block copolycarbonates | Bayer Aktiengesellschaft (DE) | 2000-12-27 | — | — | EP | disclosed |