SCHEMBL5349727

SCHEMBL5349727

COc1ccc(O)c(OC)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.54
MAPT P10636 3/20 0.54
MAPK1 P28482 2/20 0.54
TP53 P04637 2/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
HPGD P15428 1/20 0.54
ALOX15 P16050 1/20 0.54
ALOX12 P18054 1/20 0.54
HSD17B10 Q99714 1/20 0.54
HIF1A Q16665 1/20 0.50
EPAS1 Q99814 1/20 0.50
TDP1 Q9NUW8 1/20 0.47
MAOB P27338 1/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
TSHR P16473 1/20 0.44
PTGS1 P23219 1/20 0.44
TUBB1 Q9H4B7 7/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1402474 0.85 MAPT (0.61) CYP3A4MAPTMAPK1TP53KDM4E
SCHEMBL1402414 0.83 MAPT (0.48) CYP3A4MAPTMAPK1TP53KDM4E
SCHEMBL11882012 0.82 MAPT (0.48) CYP3A4MAPTMAPK1TP53KDM4E
SCHEMBL70595 0.81 MAPT (0.57) CYP3A4MAPTMAPK1TP53KDM4E
SCHEMBL27770681 0.81 MAPT (0.47) CYP3A4MAPTMAPK1TP53KDM4E
SCHEMBL9742294 0.80 KDM4E (0.65) CYP3A4MAPTMAPK1TP53KDM4E
SCHEMBL12584714 0.79 MAPT (0.46) CYP3A4MAPTMAPK1TP53KDM4E
SCHEMBL29421917 0.79 MAOB (0.45) CYP3A4MAPTMAPK1TP53KDM4E
SCHEMBL5141870 0.79 MAOB (0.45) CYP3A4MAPTMAPK1TP53KDM4E
SCHEMBL30364533 0.79 MAPT (0.46) CYP3A4MAPTMAPK1TP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114615967-B Two-component oxidation dyeing composition 花王株式会社 2024-05-14 CN disclosed
CN-115160279-B Benzopyrone compounds, pharmaceutical compositions and uses 中国药科大学 2023-11-24 CN disclosed
CN-115160279-A Benzopyrone compound, pharmaceutical composition and application 中国药科大学 2022-10-11 CN disclosed
EP-3430105-B1 CARBOGEL ANODE MATERIALS AND METHOD FOR THEIR PREPARATION UNIV JAGIELLONSKI (PL) 2022-08-31 EP disclosed
US-11117802-B2 Carbogel anode materials and method for their preperation UNIWERSYTET JAGIELLONSKI (PL) 2021-09-14 US disclosed
CN-108884394-B Carbon gel anode material and preparation method thereof 雅盖隆大学 2021-04-06 CN disclosed
US-10945991-B2 Use and pharmaceutical composition for liver fibrosis prevention and/or treatment COJET BIOTECH INC. (TW) 2021-03-16 US disclosed
US-20200129475-A1 USE AND PHARMACEUTICAL COMPOSITION FOR LIVER FIBROSIS PREVENTION AND/OR TREATMENT COJET BIOTECH INC. (TW) 2020-04-30 US disclosed
US-20190071311-A1 CARBOGEL ANODE MATERIALS AND METHOD FOR THEIR PREPERATION UNIWERSYTET JAGIELLONSKI (PL) 2019-03-07 US disclosed
EP-3430105-A1 CARBOGEL ANODE MATERIALS AND METHOD FOR THEIR PREPARATION Uniwersytet Jagiello Ski (PL) 2019-01-23 EP disclosed
US-20170014355-A1 CANNABINOID RECEPTOR TREATMENTS TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2017-01-19 US disclosed
WO-2013025984-A2 CANNABINOID RECEPTOR TREATMENTS TEMPLE UNIVERSITY (US) 2013-02-21 WO disclosed
CN-100560577-C The synthetic method of the synthetic method of wogonin and intermediate thereof and intermediate UNIV CHINA PHARMA (CN) 2009-11-18 CN disclosed
US-7285687-B2 Cannabinoids VIRGINIA COMMONWEALTH UNIVERSITY (US) 2007-10-23 US disclosed
US-7179800-B2 Such as 2-(3-methylcyclohexyl)-5-(1,1'-dimethylheptyl)-resorcinol for treatment of pain, inflammation and autoimmune disease VIRGINIA COMMONWEALTH UNIVERSITY (US) 2007-02-20 US disclosed
US-20070037890-A1 Such as 2-(3-methylcyclohexyl)-5-(1,1'-dimethylheptyl)-resorcinol for treatment of pain, inflammation and autoimmune disease VIRGINIA COMMONWEALTH UNIVERSITY (US) 2007-02-15 US disclosed
US-20050165259-A1 Such as 2-(3-methylcyclohexyl)-5-(1,1'-dimethylheptyl)-resorcinol for treatment of pain, inflammation and autoimmune disease VIRGINIA COMMONWEALTH UNIVERSITY (US) 2005-07-28 US disclosed
US-20050159449-A1 Cannabinoids VIRGINIA COMMONWEALTH UNIVERSITY (US) 2005-07-21 US disclosed
WO-2003091189-A1 CANNABINOIDS VIRGINIA COMMONWEALTH UNIVERSITY (US) 2003-11-06 WO disclosed
EP-0094769-B1 PREPARING 7-ALKOXYBENZOFURANS AND INTERMEDIATES USED THEREIN THE UPJOHN COMPANY (US) 1986-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170014355-A1 CANNABINOID RECEPTOR TREATMENTS CNR1, CNR2, GPR18 CYP3A4 1441/4885MAPT 4023/4885MAPK1 2337/4885
US-10945991-B2 Use and pharmaceutical composition for liver fibrosis prevention and/or treatment GOT1, GOT2, GYS2 CYP3A4 442/4885MAPT 4514/4885MAPK1 2593/4885
US-20050165259-A1 Such as 2-(3-methylcyclohexyl)-5-(1,1'-dimethylheptyl)-resorcinol for treatment of pain, inflammation and autoimmune disease CNR1, CNR2, HRH4 CYP3A4 596/4885MAPT 430/4885MAPK1 1021/4885
US-20050159449-A1 Cannabinoids CNR1, CNR2, OPRL1 CYP3A4 709/4885MAPT 264/4885MAPK1 1419/4885
US-20200129475-A1 USE AND PHARMACEUTICAL COMPOSITION FOR LIVER FIBROSIS PREVENTION AND/OR TREATMENT GOT1, GOT2, GYS2 CYP3A4 672/4885MAPT 4479/4885MAPK1 2708/4885
US-20070037890-A1 Such as 2-(3-methylcyclohexyl)-5-(1,1'-dimethylheptyl)-resorcinol for treatment of pain, inflammation and autoimmune disease CNR1, CNR2, HRH4 CYP3A4 596/4885MAPT 430/4885MAPK1 1021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.