Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737788 | 0.87 | — | — | |
| SCHEMBL9006983 | 0.76 | BACE1 (0.37) | BACE1 | |
| SCHEMBL5320647 | 0.71 | RXRA (0.47) | — | |
| SCHEMBL888447 | 0.71 | TSHR (0.39) | — | |
| SCHEMBL9006953 | 0.69 | AKR1B1 (0.31) | — | |
| SCHEMBL9007021 | 0.69 | SLC6A4 (0.31) | SLC6A4BACE1 | |
| SCHEMBL12478910 | 0.67 | ALDH1A1 (0.61) | — | |
| SCHEMBL5736909 | 0.66 | AKR1B1 (0.35) | BACE1 | |
| SCHEMBL433187 | 0.66 | MAPT (0.45) | — | |
| SCHEMBL4417328 | 0.66 | BACE1 (0.37) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571546-B1 | CHROMAN AND THIOCHROMANS WITH PHENYLETHYNYL SUBSTITUENTS AT THE 7-POSITION HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN INC (US) | 1996-10-16 | — | — | EP | disclosed |
| US-5346915-A | Chromans and thiochromans with phenylethynyl substituents at the 7-position having retinold-like biological activity | ALLERGAN, INC. (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0571546-A1 | CHROMAN AND THIOCHROMANS WITH PHENYLETHYNYL SUBSTITUENTS AT THE 7-POSITION HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY. | ALLERGAN INC (US) | 1993-12-01 | — | — | EP | disclosed |
| WO-1992014725-A1 | CHROMAN AND THIOCHROMANS WITH PHENYLETHYNYL SUBSTITUENTS AT THE 7-POSITION HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN, INC. (US) | 1992-09-03 | — | — | WO | disclosed |