Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28759640 | 0.80 | TSHR (0.40) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL7680467 | 0.80 | TRPM8 (0.40) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL1441712 | 0.78 | PKM (0.41) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL10382409 | 0.75 | CYP2C19 (0.39) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL28243000 | 0.75 | CYP2D6 (0.42) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL23811463 | 0.75 | CYP2D6 (0.39) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL18536298 | 0.75 | CYP2D6 (0.39) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL2254492 | 0.74 | PPIB (0.35) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL29350846 | 0.74 | PPIB (0.35) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL24043403 | 0.73 | CYP2D6 (0.38) | TSHRMEN1KMT2ACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234380-A1 | Compositions and method for treatment of chronic inflammatory diseases | SHAPIRO HOWARD K | 2008-09-25 | — | — | US | claimed |
| US-20050090553-A1 | Compositions and method for treatment of chronic inflammatory diseases | SECANT PHARMA, LLC | 2005-04-28 | — | — | US | claimed |
| US-6746678-B1 | Method of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with medicaments | SECANT PHARMA, LLC | 2004-06-08 | — | — | US | claimed |
| EP-0759750-A4 | COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES | SHAPIRO HOWARD K (US) | 1998-05-27 | — | — | EP | claimed |
| EP-0759750-A1 | COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES | SHAPIRO, Howard, K. (US) | 1997-03-05 | — | — | EP | claimed |
| WO-1995031194-A1 | COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES | SHAPIRO HOWARD K (US) | 1995-11-23 | — | — | WO | claimed |
| EP-0504017-A1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-09-16 | — | — | EP | claimed |
| US-20240052418-A1 | METHOD FOR PREDICTING A SUBJECT'S RESPONSE TO SLC MODULATOR THERAPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-02-15 | — | — | US | disclosed |
| US-11814681-B2 | Method for predicting a subjects response to SLC modulator therapy | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230200208-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | LG DISPLAY CO., LTD. (KR) | 2023-06-22 | — | — | US | disclosed |
| US-20210254158-A1 | METHOD FOR PREDICTING A SUBJECTS RESPONSE TO SLC MODULATOR THERAPY | RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. | 2021-08-19 | — | — | US | disclosed |
| CN-104606392-B | A kind of composition for the antioxidant activity increasing antioxidant | 上海交大昂立股份有限公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-108169375-A | A kind of finger-print combines the method for differentiating the propolis true and false with antioxidant activity | 上海交大昂立股份有限公司 | 2018-06-15 | — | — | CN | disclosed |
| WO-1995031194-A1 | COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES | SHAPIRO HOWARD K (US) | 1995-11-23 | — | — | WO | disclosed |
| EP-0638075-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994019335-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |
| EP-0504017-A1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-09-16 | — | — | EP | disclosed |
| US-4511685-A | Chroman derivatives and stabilized polypropylene composition | BASF AKTIENGESELLSCHAFT (DE) | 1985-04-16 | — | — | US | disclosed |
| US-4404304-A | Chroman derivatives useful as stabilizers for polypropylene and β-carotin | BASF AKTIENGESELLSCHAFT (DE) | 1983-09-13 | — | — | US | disclosed |
| US-4374258-A | PHOTOSTABILITY; HEAT AND OXIDATION RESISTANCE; ADDITION POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 1983-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230200208-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | CRY1, PPOX, ODC1 | TSHR 4271/4885MEN1 995/4885KMT2A 916/4885 |
| US-20050090553-A1 | Compositions and method for treatment of chronic inflammatory diseases | PCCA, HMGB1, PTGES | TSHR 4800/4885MEN1 4876/4885KMT2A 1830/4885 |
| US-20080234380-A1 | Compositions and method for treatment of chronic inflammatory diseases | HMGB1, PCCA, QSOX1 | TSHR 4720/4885MEN1 4870/4885KMT2A 1426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.