Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 7/20 | 0.39 |
| ▸ | BRD2 | P25440 | 7/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 7/20 | 0.39 |
| ▸ | CCKBR | P32239 | 5/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555255 | 0.82 | CBLB (0.37) | CCKBR | |
| SCHEMBL8555087 | 0.78 | BRD4 (0.41) | SENP1SCN9ABRD4BRD2BRD3 | |
| SCHEMBL8622534 | 0.77 | SENP1 (0.47) | SENP1SCN9ABRD4BRD2BRD3 | |
| SCHEMBL7544650 | 0.77 | SCN9A (0.45) | SENP1SCN9ABRD4BRD2BRD3 | |
| SCHEMBL7544642 | 0.77 | SCN9A (0.45) | SENP1SCN9ABRD4BRD2BRD3 | |
| SCHEMBL7551316 | 0.73 | BRD4 (0.40) | SENP1BRD4BRD2BRD3CCKBR | |
| SCHEMBL7551310 | 0.73 | BRD4 (0.40) | SENP1BRD4BRD2BRD3CCKBR | |
| SCHEMBL8558106 | 0.70 | SENP1 (0.49) | SENP1BRD4BRD2BRD3CCKBR | |
| SCHEMBL6301555 | 0.70 | SCN9A (0.57) | SENP1SCN9ABRD4BRD2BRD3 | |
| SCHEMBL5800119 | 0.68 | BDKRB1 (0.59) | SENP1SCN9ABRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569654-A | ADMINISTERING AS ANTAGONISTS OF GASTRIN AND CHOLECYSTOKININ | GLAXO GROUP LIMITED (GB) | 1996-10-29 | — | — | US | disclosed |