Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.47 |
| ▸ | CCKBR | P32239 | 8/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.39 |
| ▸ | BRD2 | P25440 | 4/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555248 | 0.82 | OXTR (0.41) | CCKBROXTRDRD4BDKRB1 | |
| SCHEMBL8555082 | 0.80 | SENP1 (0.44) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL9007259 | 0.79 | CCKBR (0.52) | CCKBR | |
| SCHEMBL8552793 | 0.79 | CCKBR (0.48) | CCKBRBDKRB1 | |
| SCHEMBL8558106 | 0.78 | SENP1 (0.49) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL9007263 | 0.77 | SENP1 (0.42) | SENP1CCKBRSCN9ABRD4BRD2 | |
| SCHEMBL7544642 | 0.77 | SCN9A (0.45) | SENP1CCKBRSCN9ABRD4BRD2 | |
| SCHEMBL7544650 | 0.77 | SCN9A (0.45) | SENP1CCKBRSCN9ABRD4BRD2 | |
| SCHEMBL9868359 | 0.76 | SENP1 (0.67) | SENP1CCKBRSCN9ABRD4BRD2 | |
| SCHEMBL1388598 | 0.74 | CCKBR (0.59) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |
| US-5569654-A | ADMINISTERING AS ANTAGONISTS OF GASTRIN AND CHOLECYSTOKININ | GLAXO GROUP LIMITED (GB) | 1996-10-29 | — | — | US | disclosed |