Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.41 |
| ▸ | BRD2 | P25440 | 7/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 7/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.39 |
| ▸ | CCKBR | P32239 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555082 | 0.79 | SENP1 (0.44) | BRD4BRD2BRD3SENP1CCKBR | |
| SCHEMBL9007263 | 0.78 | SENP1 (0.42) | BRD4BRD2BRD3SENP1CCKBR | |
| SCHEMBL8555255 | 0.75 | CBLB (0.37) | CCKBROXTR | |
| SCHEMBL8558106 | 0.74 | SENP1 (0.49) | BRD4BRD2BRD3SENP1CCKBR | |
| SCHEMBL8553128 | 0.71 | CBLB (0.56) | CCKBR | |
| SCHEMBL9007333 | 0.69 | ENPP2 (0.35) | ENPP2SCN9AABL1RIN1CACNA1G | |
| SCHEMBL8595286 | 0.66 | CCKBR (0.46) | CCKBR | |
| SCHEMBL8622534 | 0.66 | SENP1 (0.47) | BRD4BRD2BRD3SENP1CCKBR | |
| SCHEMBL6301555 | 0.66 | SCN9A (0.57) | BRD4BRD2BRD3SENP1CCKBR | |
| SCHEMBL4420621 | 0.66 | SCN9A (0.69) | BRD4BRD2BRD3SENP1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |