Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 8/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.34 |
| ▸ | NOTCH3 | Q9UM47 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007288 | 0.84 | CCKBR (0.45) | CCKBR | |
| SCHEMBL8555480 | 0.84 | CCKBR (0.38) | CCKBRNOTCH1NOTCH3 | |
| SCHEMBL9007263 | 0.82 | SENP1 (0.42) | CCKBR | |
| SCHEMBL8555087 | 0.75 | BRD4 (0.41) | OXTRCCKBR | |
| SCHEMBL8646939 | 0.66 | CCKAR (0.55) | CCKBR | |
| SCHEMBL1388679 | 0.66 | CCKBR (0.53) | CCKBR | |
| SCHEMBL8558106 | 0.66 | SENP1 (0.49) | OXTRCCKBRBDKRB1 | |
| SCHEMBL8552604 | 0.64 | CCKBR (0.48) | CCKBR | |
| SCHEMBL8553824 | 0.64 | POLB (0.41) | CBLBOXTRLMNA | |
| SCHEMBL8595286 | 0.64 | CCKBR (0.46) | LMNACCKBRBDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |
| US-5569654-A | ADMINISTERING AS ANTAGONISTS OF GASTRIN AND CHOLECYSTOKININ | GLAXO GROUP LIMITED (GB) | 1996-10-29 | — | — | US | disclosed |