Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 7/20 | 0.66 |
| ▸ | CYBB | P04839 | 1/20 | 0.66 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.66 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007359 | 0.87 | NOX1 (0.68) | NOX1CYBBNOX3NOX4ALDH1A1 | |
| SCHEMBL8879904 | 0.82 | NOX1 (0.66) | NOX1CYBBNOX3NOX4ALDH1A1 | |
| SCHEMBL10372692 | 0.81 | NOX1 (0.84) | NOX1CYBBNOX3NOX4ALDH1A1 | |
| SCHEMBL30811565 | 0.81 | NOX1 (0.84) | NOX1CYBBNOX3NOX4ALDH1A1 | |
| SCHEMBL560225 | 0.80 | NOX1 (1.00) | NOX1CYBBNOX3NOX4ALDH1A1 | |
| Phenothiazine SCHEMBL6532335 | 0.80 | NOX1 (1.00) | NOX1CYBBNOX3NOX4ALDH1A1 | |
| SCHEMBL29475150 | 0.80 | NOX1 (1.00) | NOX1CYBBNOX3NOX4ALDH1A1 | |
| SCHEMBL7970097 | 0.79 | ALDH1A1 (1.00) | NOX1CYBBNOX3NOX4ALDH1A1 | |
| Benzene SCHEMBL29242186 | 0.78 | NOX1 (0.97) | NOX1CYBBNOX3NOX4ALDH1A1 | |
| SCHEMBL11880410 | 0.73 | NOX1 (0.49) | NOX1CYBBNOX3NOX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589474-A | Dibenzothiazepinthione as antiviral agents | GLAXO WELLCOME INC. (US) | 1996-12-31 | — | — | US | disclosed |
| EP-0583317-A1 | DIBENZOTHIAZEPINTHIONE AS ANTIVIRAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-02-23 | — | — | EP | disclosed |
| WO-1992019607-A1 | DIBENZOTHIAZEPINTHIONE AS ANTIVIRAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-11-12 | — | — | WO | disclosed |