Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030601 | 0.78 | GAA (0.43) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL28556815 | 0.75 | ALDH1A1 (0.52) | L3MBTL1SIRT2SIRT1 | |
| SCHEMBL9007658 | 0.73 | ACE2 (0.40) | L3MBTL1ACE2PPARGPPARA | |
| SCHEMBL5030597 | 0.73 | GAA (0.44) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL9063428 | 0.73 | L3MBTL1 (0.51) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL17381379 | 0.72 | CETP (0.54) | L3MBTL1SIRT2SIRT1 | |
| SCHEMBL7537791 | 0.72 | CETP (0.54) | L3MBTL1SIRT2SIRT1 | |
| SCHEMBL27369903 | 0.72 | CETP (0.54) | L3MBTL1SIRT2SIRT1 | |
| SCHEMBL29078539 | 0.72 | CYP3A4 (0.37) | GAAKCNH2S1PR2S1PR1S1PR3 | |
| SCHEMBL2546373 | 0.72 | PPARG (0.48) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516006-B1 | 4,4'-Biphenylenediphosphonite compound and use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-10-23 | — | — | EP | claimed |