Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007685 | 0.81 | FAAH (0.40) | EPHX2ALDH1A1 | |
| SCHEMBL3125775 | 0.80 | GAA (0.47) | CYP3A4MAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL5083341 | 0.75 | CYP1A2 (0.42) | CYP3A4MAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL25311713 | 0.75 | RXRA (0.51) | ACE2NR1H4EPHX2RXRARXRB | |
| SCHEMBL9706399 | 0.73 | ALDH1A1 (0.45) | NR1H4MAPTALDH1A1L3MBTL1POLB | |
| SCHEMBL11709829 | 0.73 | ACE2 (0.42) | ACE2EPHX2CYP3A4MAPTALDH1A1 | |
| SCHEMBL9420233 | 0.71 | APP (0.47) | ACE2KMT2A | |
| SCHEMBL3125768 | 0.71 | GAA (0.50) | CYP3A4MAPTALDH1A1MAPK1CA1 | |
| SCHEMBL28777953 | 0.71 | KDM4E (0.55) | MAPTALDH1A1CA1CA2POLB | |
| SCHEMBL27968590 | 0.70 | GAA (0.49) | MAPTALDH1A1L3MBTL1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516006-B1 | 4,4'-Biphenylenediphosphonite compound and use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-10-23 | — | — | EP | claimed |