Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 7/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007658 | 0.81 | ACE2 (0.40) | ALDH1A1EPHX2 | |
| SCHEMBL4795817 | 0.78 | GAA (0.45) | TSHRALDH1A1LMNA | |
| SCHEMBL439039 | 0.76 | DGKA (0.50) | NAAACNR2EPHX2CNR1 | |
| SCHEMBL26958103 | 0.74 | ALDH1A1 (0.58) | FAAHNAAATSHRALDH1A1LMNA | |
| SCHEMBL14247167 | 0.74 | CNR2 (0.47) | CNR2TSHRALDH1A1CNR1 | |
| SCHEMBL28003839 | 0.73 | ALDH1A1 (0.60) | FAAHNAAATSHRALDH1A1LMNA | |
| SCHEMBL2184521 | 0.71 | APP (0.52) | CNR2CNR1 | |
| SCHEMBL9169755 | 0.71 | APP (0.52) | CNR2CNR1 | |
| SCHEMBL3468016 | 0.71 | APP (0.52) | CNR2CNR1 | |
| SCHEMBL9168908 | 0.71 | APP (0.52) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516006-B1 | 4,4'-Biphenylenediphosphonite compound and use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-10-23 | — | — | EP | claimed |
| US-5300257-A | Stabilizers | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-04-05 | — | — | US | claimed |
| EP-0516006-A1 | 4,4'-Biphenylenediphosphonite compound and use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-12-02 | — | — | EP | claimed |