Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | EEF2K | O00418 | 1/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.50 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007877 | 0.83 | POLB (0.50) | ALDH1A1SMN1; SMN2KMT2ALMNAHTR6 | |
| SCHEMBL11722434 | 0.77 | SLC40A1 (0.54) | TDP1MEN1KMT2ALMNAEDNRA | |
| SCHEMBL6557184 | 0.73 | MAPT (0.63) | ALDH1A1TDP1CYP3A4SMN1; SMN2CYP2C9 | |
| SCHEMBL14837791 | 0.73 | NTRK1 (0.37) | — | |
| Sulfaclomide SCHEMBL29388430 | 0.72 | SMN1; SMN2 (0.66) | ALDH1A1TDP1CYP3A4SMN1; SMN2CYP2C9 | |
| Sulfaperin SCHEMBL151755 | 0.72 | LMNA (0.70) | ALDH1A1TDP1CYP3A4SMN1; SMN2CYP2C9 | |
| Sulfanilamide SCHEMBL27840602 | 0.72 | CA2 (0.52) | TDP1AGO2TSHRHTR6 | |
| SCHEMBL13457574 | 0.71 | TDP1 (0.50) | ALDH1A1TDP1CYP3A4SMN1; SMN2CYP2C9 | |
| Sulfaperin SCHEMBL16416441 | 0.71 | LMNA (0.68) | ALDH1A1TDP1CYP3A4SMN1; SMN2CYP2C9 | |
| Sulfaperin SCHEMBL9418724 | 0.71 | LMNA (0.68) | ALDH1A1TDP1CYP3A4SMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236002-B2 | Pharmaceutical composition comprising a medicament and a water-swellable polymer | MALLINCKRODT VETERINARY INC (US) | 1996-10-23 | — | — | EP | disclosed |
| EP-0416722-B1 | Pharmaceutical compositions having differential drug release rate | PITMAN MOORE LTD (GB) | 1994-09-28 | — | — | EP | disclosed |
| US-5273970-A | Administering baquiloprim or a salt thereof to treat Toxoplasma gondii infection | COOPERS ANIMAL HEALTH LIMITED (GB) | 1993-12-28 | — | — | US | disclosed |
| US-5190760-A | Drugs for bactericides and anthelmintics | COOPERS ANIMAL HEALTH LIMITED (GB) | 1993-03-02 | — | — | US | disclosed |
| EP-0136438-B1 | GANGLIOSIDE DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-29 | — | — | EP | disclosed |
| EP-0441475-A2 | Baquiloprim for treating protozoal infections | PITMAN-MOORE LIMITED (GB) | 1991-08-14 | — | — | EP | disclosed |
| EP-0416722-A2 | Pharmaceutical compositions having differential drug release rate | PITMAN-MOORE LIMITED (GB) | 1991-03-13 | — | — | EP | disclosed |
| EP-0096214-B1 | ANTIBACTERIAL PYRIMIDINE COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-02-27 | — | — | EP | disclosed |
| US-4831021-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1989-05-16 | — | — | US | disclosed |
| US-4795639-A | ANTI-PROTOZOA TREATMENT | BURROUGHS WELLCOME CO. (US) | 1989-01-03 | — | — | US | disclosed |
| EP-0078002-B1 | HERBICIDES CONTAINING TRIAZOLO(2,3-B)QUINAZOLONE AS ACTIVE INGREDIENT, AND THEIR USE AS PLANT GROWTH REGULATORS | BASF Aktiengesellschaft (DE) | 1985-08-21 | — | — | EP | disclosed |
| EP-0136438-A2 | Ganglioside derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-04-10 | — | — | EP | disclosed |
| US-4438267-A | ANTIBACTERIAL AGENTS | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 1984-03-20 | — | — | US | disclosed |
| EP-0096214-A1 | Antibacterial pyrimidine compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-12-21 | — | — | EP | disclosed |
| EP-0078002-A2 | Herbicides containing triazolo(2,3-b)quinazolone as active ingredient, and their use as plant growth regulators | BASF Aktiengesellschaft (DE) | 1983-05-04 | — | — | EP | disclosed |
| EP-0078003-A2 | Thiazolo (2,3-b)-quinazolones and process for their preparation | BASF Aktiengesellschaft (DE) | 1983-05-04 | — | — | EP | disclosed |
| EP-0054756-A2 | Antibacterial benzylpyrimidines | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-06-30 | — | — | EP | disclosed |
| EP-0006987-A1 | 2,4-Diamino-5-benzylpyrimidines, especially for the treatment of microbial infections, pharmaceutical compositions containing these compounds and processes for preparing these compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1980-01-23 | — | — | EP | disclosed |
| US-4156725-A | MICROBIOCIDES | BURROUGHS WELLCOME CO. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4073786-A | BACTERIOSTAT | BURROUGHS WELLCOME CO. (US) | 1978-02-14 | — | — | US | disclosed |