Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29109505 | 0.94 | GGT1 (0.33) | LMNACNR1ADRA1ATDP1KDM4E | |
| Alcohol SCHEMBL9008042 | 0.89 | CA12 (0.39) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL8940848 | 0.84 | GGT1 (0.35) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL24982636 | 0.80 | — | — | |
| SCHEMBL28988287 | 0.80 | SIGMAR1 (0.33) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL16697215 | 0.79 | CA12 (0.38) | LMNATDP1KDM4EGGT1 | |
| SCHEMBL29736046 | 0.77 | CA12 (0.36) | LMNATDP1KDM4EGGT1 | |
| SCHEMBL16343267 | 0.77 | LMNA (0.38) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL9295335 | 0.76 | ALDH1A1 (0.32) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL15319486 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584629-B1 | Polymers based on conjugated dienes | BASF AG (DE) | 1996-10-23 | — | — | EP | disclosed |
| EP-0584629-A1 | Polymers based on conjugated dienes | BASF Aktiengesellschaft (DE) | 1994-03-02 | — | — | EP | disclosed |