SCHEMBL9008257

SCHEMBL9008257

CC(C)(C)c1cc(O)c(Cc2cc(Cl)c(C(C)(C)C)cc2O)cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 6/20 0.48
▸ ALOX15 P16050 5/20 0.48
▸ ALDH1A1 P00352 5/20 0.48
▸ MAPT P10636 3/20 0.48
▸ KDM4E B2RXH2 1/20 0.48
▸ CYP1A2 P05177 1/20 0.48
▸ ATP2A2 P16615 1/20 0.48
▸ ATP2A3 Q93084 1/20 0.48
▸ HIF1A Q16665 5/20 0.44
▸ CYP2C9 P11712 5/20 0.44
▸ CYP2C19 P33261 4/20 0.44
▸ TP53 P04637 3/20 0.44
▸ HSPA5 P11021 3/20 0.44
▸ LMNA P02545 4/20 0.41
▸ CYP3A4 P08684 3/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ USP2 O75604 2/20 0.41
▸ CASP1 P29466 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ HPGD P15428 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16736913 0.86 SMN1; SMN2 (0.46) SMN1; SMN2ALOX15ALDH1A1MAPTKDM4E
SCHEMBL16736854 0.83 HMGCR (0.44) SMN1; SMN2ALOX15ALDH1A1MAPTKDM4E
SCHEMBL9054498 0.83 SMN1; SMN2 (0.56) SMN1; SMN2ALOX15ALDH1A1MAPTKDM4E
SCHEMBL12733114 0.81 ALOX15 (0.68) SMN1; SMN2ALOX15ALDH1A1MAPTKDM4E
SCHEMBL16736605 0.80 TYR (0.46) SMN1; SMN2ALOX15ALDH1A1MAPTKDM4E
SCHEMBL16736702 0.79 ALOX15 (0.71) SMN1; SMN2ALOX15ALDH1A1MAPTKDM4E
SCHEMBL10907968 0.79 ALDH1A1 (0.56) SMN1; SMN2ALOX15ALDH1A1MAPTKDM4E
SCHEMBL25692882 0.78 SMN1; SMN2 (0.41) SMN1; SMN2ALOX15ALDH1A1MAPTKDM4E
SCHEMBL2931006 0.78 ALDH1A1 (0.50) SMN1; SMN2ALOX15ALDH1A1MAPTKDM4E
SCHEMBL29405765 0.78 ALDH1A1 (0.50) SMN1; SMN2ALOX15ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0331095-B1 Improving stability at moderate temperatures of motor vehicle components shaped from polyvinyl chloride resin compositions WITCO CORP (US) 1996-10-09 — — EP disclosed
EP-0313676-B1 Bis-(2,2,6,6-tetramethyl-piperidyl) diimides as light stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO LTD (JP) 1994-01-26 — — EP disclosed
EP-0184203-B1 VINYL BENZYL 2,2,6,6-TETRAMETHYL PIPERIDINES ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1992-04-15 — — EP disclosed
EP-0188236-B1 POLYACETAL RESIN COMPOSITIONS HAVING IMPROVED RESISTANCE TO DETERIORATION WHEN EXPOSED TO LIGHT AND CONTAINING ALKYLIDENE BIS(BENZOTRIAZOLYL PHENOLS) ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1992-04-01 — — EP disclosed
EP-0209126-B1 HYDROCARBYL(POLYPHENOL)-POLY(2,2,6,6-TETRAMETHYL PIPERIDYL-1,3,5-TRIAZINES) AS STABILIZERS FOR SYNTHETIC POLYMER COMPOSITIONS ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1992-01-02 — — EP disclosed
US-4957954-A TETRAMETHYPIPERIDINYL COMPOUND AND PERCHLORATE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-18 — — US disclosed
EP-0047894-B2 HOMOGENEOUS STORAGE-STABLE LIQUID BARIUM-CADMIUM-TRIPHOSPHITE STABILIZER SYSTEMS FOR POLYVINYL CHLORIDE RESINS Argus Chemical Corporation (US) 1990-09-05 — — EP disclosed
US-4950704-A DIKETONE AS HEAT STABILIZER ARGUS CHEMICAL CORPORATION (US) 1990-08-21 — — US disclosed
US-4910238-A Photostable polyvinyl chloride ADEKA ARGUS CHEMICAL CO. LTD. (JP) 1990-03-20 — — US disclosed
US-4898688-A PHOTOSTABILITY, HEAT RESISTANCE, OXIDATION RESISTANCE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-02-06 — — US disclosed
EP-0046161-A2 Stabilized Polyvinylhalide resin PHOENIX CHEMICAL CORPORATION (US) 1982-02-24 — — EP disclosed
EP-0040286-A2 Polyvinyl halide resin compositions containing 1,3 Dicarbonyl compounds PHOENIX CHEMICAL CORPORATION (US) 1981-11-25 — — EP disclosed
EP-0038876-A1 2,6-Di-tertiary butyl phenyl pentaerythritol spiro bis-phosphites enhancing the stability to heat and light of synthetic resins, stabilizer compositions comprising phenolic antioxidants and such phosphites, and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-11-04 — — EP disclosed
US-4279805-A Alkylene-bis-thioalkanoic acid amide stabilizers for synthetic resins and synthetic resin compositions containing the same ARGUS CHEMICAL CORPORATION (US) 1981-07-21 — — US disclosed
US-4222931-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl ether alcohol or ether, phosphonic acid ester and phenolic antioxidant ARGUS CHEMICAL CORPORATION (US) 1980-09-16 — — US disclosed
US-4219463-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, β-thioalkyl propionic acid ester and phenol ARGUS CHEMICAL CORPORATION (US) 1980-08-26 — — US disclosed
US-4210577-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, phosphonic acid ester and phenol ARGUS CHEMICAL CORPORATION (US) 1980-07-01 — — US disclosed
US-4209431-A OXIDATION AND HEAT RESISTANCE WITCO CHEMICAL CORPORATION (US) 1980-06-24 — — US disclosed
US-4080364-A Stabilization of polyolefins against degradative deterioration as a result of exposure to light and air at elevated temperatures ARGUS CHEMICAL CORPORATION (US) 1978-03-21 — — US disclosed
US-3997551-A OXIDATION RESISTANCE, STABILIZE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1976-12-14 — — US disclosed
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