Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | FGB | P02675 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008523 | 0.85 | TTR (0.43) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11625180 | 0.83 | MAOB (0.35) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL11619908 | 0.80 | PTPRC (0.35) | MAPTMEN1KMT2APTPRCPTPN1 | |
| SCHEMBL187940 | 0.78 | ALDH1A1 (0.54) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6608296 | 0.76 | GRK6 (0.45) | MAPTALDH1A1KDM4ETDP1RAB9A | |
| SCHEMBL8996320 | 0.75 | EGFR (0.45) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL3044550 | 0.75 | HSD17B10 (0.47) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10765716 | 0.75 | KDM4E (0.40) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL705661 | 0.75 | MAPT (0.49) | MAPTALDH1A1KDM4EMEN1TDP1 | |
| SCHEMBL8326642 | 0.74 | LMNA (0.47) | ALDH1A1KDM4ETDP1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484935-A | Pharmaceutical compounds | LILLY INDUSTRIES LIMITED (GB) | 1996-01-16 | — | — | US | claimed |
| EP-0638562-A1 | Anthraquinone derivatives useful in the treatment of cancer and osteoartritis | LILLY INDUSTRIES LIMITED (GB) | 1995-02-15 | — | — | EP | claimed |
| JP-7101944-A | — | — | None | — | — | JP | disclosed |
| US-5484935-A | Pharmaceutical compounds | LILLY INDUSTRIES LIMITED (GB) | 1996-01-16 | — | — | US | disclosed |
| JP-H07101944-A | 9,10-DIHYDRO-5,8-DIMETHOXY-9,10-DIOXOANTRACENE-2-YLS AND SALTS OR ESTERS THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | LILLY IND LTD | 1995-04-18 | — | — | JP | disclosed |
| EP-0638562-A1 | Anthraquinone derivatives useful in the treatment of cancer and osteoartritis | LILLY INDUSTRIES LIMITED (GB) | 1995-02-15 | — | — | EP | disclosed |