Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MGAM | O43451 | 2/20 | 0.33 |
| ▸ | SI | P14410 | 2/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19809404 | 0.82 | SERPINE1 (0.43) | CYP3A4ALOX15HSD17B10GAAKMT2A | |
| SCHEMBL6856186 | 0.73 | PPM1B (0.53) | CYP3A4ALOX15HSD17B10BRD4GAA | |
| SCHEMBL19809453 | 0.72 | KMT2A (0.45) | CYP3A4ALOX15HSD17B10GAAKMT2A | |
| SCHEMBL9635994 | 0.71 | ALDH1A1 (0.52) | CYP3A4ALOX15HSD17B10KMT2AMEN1 | |
| SCHEMBL19809269 | 0.70 | KMT2A (0.42) | CYP3A4ALOX15HSD17B10GAAKMT2A | |
| SCHEMBL23924225 | 0.68 | CYP3A4 (1.00) | CYP3A4ALOX15HSD17B10BRD4GAA | |
| SCHEMBL29549758 | 0.68 | CYP3A4 (1.00) | CYP3A4ALOX15HSD17B10BRD4GAA | |
| SCHEMBL105866 | 0.68 | CYP3A4 (1.00) | CYP3A4ALOX15HSD17B10BRD4GAA | |
| SCHEMBL29365557 | 0.68 | CYP3A4 (1.00) | CYP3A4ALOX15HSD17B10BRD4GAA | |
| SCHEMBL28822419 | 0.66 | ALOX15 (0.85) | CYP3A4ALOX15HSD17B10BRD4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534614-A | Method for the preparation of amide oligomers and polybenzazole polymers therefrom | THE DOW CHEMICAL COMPANY (US) | 1996-07-09 | — | — | US | disclosed |
| US-5322916-A | Method for the preparation of amide oligomers and polybenzazole polymers therefrom | THE DOW CHEMICAL COMPANY (US) | 1994-06-21 | — | — | US | disclosed |
| US-4939215-A | CHEMICAL AND RADIATION RESISTANCE; AIRCRAFT, ELECTRONICS | HOECHST CELANESE CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |
| US-4845183-A | MOLDING MATERIALS; FOR DIELECTRICS OR COATING SOLUTIONS; TOUGHNESS, FLEXIBILITY, TRANSPARENT | HOECHST CELANESE CORPORATION (US) | 1989-07-04 | — | — | US | disclosed |
| EP-0317942-A2 | Heat resistant polyamides and polybenzoxazoles from bis-[(aminohydroxyphenyl hexafluoro-isopropyl] diphenyl ethers | HOECHST CELANESE CORPORATION (US) | 1989-05-31 | — | — | EP | disclosed |