Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951656 | 0.85 | DRD2 (0.40) | MTNR1AMTNR1BHTTHSD17B10DRD2 | |
| SCHEMBL24414605 | 0.85 | KDM4E (0.47) | MTNR1AMTNR1BHTTHSD17B10ALDH1A1 | |
| SCHEMBL3414185 | 0.85 | MTNR1A (0.46) | MTNR1AMTNR1BMAPK1HTTHSD17B10 | |
| SCHEMBL18935522 | 0.84 | MTNR1A (0.51) | MTNR1AMTNR1BMAPK1HTTHSD17B10 | |
| SCHEMBL3417837 | 0.83 | MTNR1A (0.50) | MTNR1AMTNR1BMAPK1HTTHSD17B10 | |
| SCHEMBL13262984 | 0.82 | IRAK4 (0.46) | MTNR1A | |
| SCHEMBL18917701 | 0.81 | MTNR1A (0.48) | MTNR1AMTNR1BMAPK1HTTHSD17B10 | |
| SCHEMBL1435781 | 0.81 | NPY5R (0.42) | HTTHSD17B10DRD2RORCALDH1A1 | |
| SCHEMBL1435785 | 0.81 | NPY5R (0.42) | HTTHSD17B10DRD2RORCALDH1A1 | |
| SCHEMBL27844158 | 0.80 | NPY5R (0.45) | HTTHSD17B10RORCALDH1A1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510359-A | VASOCONSTRUCTION | MERCK SHARP & DOHME LTD. (GB) | 1996-04-23 | — | — | US | disclosed |