Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467553 | 0.88 | KDM4E (0.41) | NPY5RALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL8029435 | 0.86 | ATM (0.53) | NPY5RALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL2470686 | 0.84 | MAPT (0.48) | NPY5RALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL23810852 | 0.81 | NTSR1 (0.51) | HDAC6ATMROCK2 | |
| SCHEMBL13836584 | 0.81 | NTSR1 (0.51) | ALDH1A1KDM4EHDAC6ATMROCK2 | |
| SCHEMBL9009161 | 0.80 | MTNR1A (0.47) | NPY5RALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL3465527 | 0.80 | KMT2A (0.55) | NPY5RALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL5069199 | 0.80 | PLA2G4A (0.55) | KDM4EHDAC6ATMROCK2PPARD | |
| SCHEMBL19470070 | 0.79 | PLA2G4A (0.43) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL1435785 | 0.78 | NPY5R (0.42) | NPY5RALDH1A1KDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102245602-B | Oxadiazole fused heterocyclic derivatives useful for the treatment of multiple sclerosis | MERCK SERONO SA | 2014-09-10 | — | — | CN | disclosed |
| CN-102245602-A | Oxadiazole fused heterocyclic derivatives useful for the treatment of multiple sclerosis | MERCK SERONO SA | 2011-11-16 | — | — | CN | disclosed |