Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900858 | 0.83 | HTT (0.36) | HTTSMN1; SMN2KMT2APDE4BBACE1 | |
| SCHEMBL16953755 | 0.82 | KCNH2 (0.39) | KMT2ASLC6A4KCNH2ALDH1A1MEN1 | |
| SCHEMBL16959674 | 0.78 | ALDH1A1 (0.47) | HTTSMN1; SMN2KMT2APDE4BBACE1 | |
| SCHEMBL900981 | 0.78 | KMT2A (0.40) | HTTKMT2APDE4BBACE1SLC6A4 | |
| SCHEMBL16955540 | 0.78 | ALDH1A1 (0.39) | HTTSMN1; SMN2KMT2ASLC6A4ALDH1A1 | |
| SCHEMBL885349 | 0.76 | DRD1 (0.42) | HTTSMN1; SMN2KMT2ASLC6A2SLC6A4 | |
| SCHEMBL17337987 | 0.75 | CA3 (0.46) | HTTSMN1; SMN2KMT2APDE4BSLC6A2 | |
| SCHEMBL30599536 | 0.75 | PKM (0.47) | HTTSMN1; SMN2KMT2APDE4BSLC6A2 | |
| SCHEMBL31540259 | 0.75 | ALDH1A1 (0.41) | HTTSMN1; SMN2KMT2APDE4BBACE1 | |
| SCHEMBL900934 | 0.75 | BACE1 (0.43) | KMT2ABACE1APPSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |