Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900933 | 0.83 | HTT (0.36) | HTTSMN1; SMN2KMT2ASLC6A2SLC6A4 | |
| SCHEMBL28043602 | 0.78 | GRIN2B (0.40) | HTTSMN1; SMN2KMT2AKCNH2ALDH1A1 | |
| SCHEMBL900973 | 0.78 | KMT2A (0.37) | HTTSMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL6024046 | 0.76 | PDE2A (0.32) | HTTSMN1; SMN2PDE2APDE10A | |
| SCHEMBL885349 | 0.76 | DRD1 (0.42) | HTTSMN1; SMN2KMT2ASLC6A2SLC6A4 | |
| SCHEMBL30019983 | 0.75 | RXRA (0.41) | HTTSMN1; SMN2KMT2ASLC6A2SLC6A4 | |
| SCHEMBL900859 | 0.75 | ALDH1A1 (0.39) | HTTSMN1; SMN2KMT2ASLC6A4KCNH2 | |
| SCHEMBL3819565 | 0.75 | RXRA (0.41) | HTTSMN1; SMN2KMT2ASLC6A2SLC6A4 | |
| SCHEMBL20639120 | 0.75 | CA3 (0.41) | HTTSMN1; SMN2KMT2ASLC6A2SLC6A4 | |
| SCHEMBL2313110 | 0.75 | ALDH1A1 (0.46) | HTTSMN1; SMN2KMT2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026672-A1 | HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |