Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900981 | 0.84 | KMT2A (0.40) | KMT2AMAPTMEN1PDE4APPARG | |
| SCHEMBL900858 | 0.78 | HTT (0.36) | KMT2AMAPTLMNAHTTALDH1A1 | |
| SCHEMBL6023181 | 0.77 | PDE4A (0.33) | KMT2AMAPTMEN1PDE4ALMNA | |
| SCHEMBL28323408 | 0.76 | KMT2A (0.37) | KMT2AMAPTMEN1PDE4ALMNA | |
| SCHEMBL8812557 | 0.76 | ALDH1A1 (0.46) | KMT2AMAPTMEN1PDE4ALMNA | |
| SCHEMBL900975 | 0.76 | GAA (0.44) | KMT2AMAPTMEN1LMNAHTT | |
| SCHEMBL680002 | 0.76 | HSD17B10 (0.45) | KMT2AMAPTMEN1PDE4ALMNA | |
| SCHEMBL14018146 | 0.76 | L3MBTL1 (0.39) | KMT2AMAPTMEN1PDE4APPARA | |
| SCHEMBL14297591 | 0.73 | HTT (0.40) | KMT2AMEN1LMNAHTTTSHR | |
| SCHEMBL97202 | 0.72 | TRPV4 (0.50) | KMT2AMEN1LMNAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |
| EP-0075117-B1 | 2H-1,2,4,6-THIATRIAZINE-1,1-DIOXIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1985-03-13 | — | — | EP | disclosed |
| US-4428766-A | 2N-1,2,4,6,Thiatriazine-1,1-dioxides and their use for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| US-4343648-A | 6H-1,2,4,6-THIATRIAZINE-1,1-DIOXIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-10 | — | — | US | disclosed |